Optical measurements of dentritic calcium currents
Fluorescence image of a mouse cerebellar Purkinje neuron.
The red and blue traces are the local changes of membrane potential and of intracellular calcium concentration recorded optically
The white trace is the membrane potential change associated with a climbing fibre synaptic potential recorded with a patch electrodie.
Our team is exploring the role and function of voltage-gated calcium channels expressed in neuronal dendrites, but also other channels including sodium and potassium channels. We investigate different neurons in various areas of the brain.
Our research activity is carried on in collaboration with other scientists within the Labex ICST or outside this consortium.
A partial list of our current collaborators includes: